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1

Overproduction and analysis of eukaryotic multiprotein complexes in Escherichia coli using a dual-vector strategy

Jeff Finkelstein, Edwin Antony, Manju M Hingorani, Michael O’Donnell

Journal:

Analytical Biochemistry

Année:

2003

Langue:

english

Fichier:

PDF, 335 KB

english, 2003

2

10.1038/35036044

Hingorani, Manju M., O'Donnell, Mike

Journal:

Nature Reviews Molecular Cell Biology

Année:

2000

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2000

3

DNA is bound within the central hole to one or two of the six subunits of the T7 DNA helicase

Yu, Xiong, Hingorani, Manju M., Patel, Smita S., Egelman, Edward H.

Journal:

Natural Structural Biology

Année:

1996

Fichier:

PDF, 830 KB

1996

4

TIRF(ing) reveals Msh2-Msh6 surfing on DNA

Hingorani, Manju M

Journal:

Nature Structural and Molecular Biology

Année:

2007

Langue:

english

Fichier:

PDF, 273 KB

english, 2007

5

Large conformational changes in MutS during DNA scanning, mismatch recognition and repair signalling

Qiu, Ruoyi, DeRocco, Vanessa C, Harris, Credle, Sharma, Anushi, Hingorani, Manju M, Erie, Dorothy A, Weninger, Keith R

Journal:

The EMBO Journal

Année:

2012

Langue:

english

Fichier:

PDF, 1.31 MB

english, 2012

6

Toroidal proteins: Running rings around DNA

Manju M Hingorani, Mike O'Donnell

Journal:

Current Biology

Année:

1998

Langue:

english

Fichier:

PDF, 99 KB

english, 1998

7

Sliding clamps: A (tail)ored fit

Manju M. Hingorani, Mike O’Donnell

Journal:

Current Biology

Année:

2000

Langue:

english

Fichier:

PDF, 265 KB

english, 2000

8

Contribution of Msh2 and Msh6 subunits to the asymmetric ATPase and DNA mismatch binding activities of Saccharomyces cerevisiae Msh2–Msh6 mismatch repair protein

Edwin Antony, Sapna Khubchandani, Siying Chen, Manju M. Hingorani

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 452 KB

english, 2006

9

Dual Functions, Clamp Opening and Primer-Template Recognition, Define a Key Clamp Loader Subunit

Maria Magdalena Coman, Mi Jin, Razvan Ceapa, Jeff Finkelstein, Michael O'Donnell, Brian T. Chait, Manju M. Hingorani

Journal:

Journal of Molecular Biology

Année:

2004

Langue:

english

Fichier:

PDF, 799 KB

english, 2004

10

The Effects of Nucleotides on MutS-DNA Binding Kinetics Clarify the Role of MutS ATPase Activity in Mismatch Repair

Emily Jacobs-Palmer, Manju M. Hingorani

Journal:

Journal of Molecular Biology

Année:

2007

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2007

11

Mechanism of ATP-Driven PCNA Clamp Loading by S. cerevisiae RFC

Siying Chen, Mikhail K. Levin, Miho Sakato, Yayan Zhou, Manju M. Hingorani

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 1.30 MB

english, 2009

12

A Central Swivel Point in the RFC Clamp Loader Controls PCNA Opening and Loading on DNA

Miho Sakato, Mike O'Donnell, Manju M. Hingorani

Journal:

Journal of Molecular Biology

Année:

2012

Langue:

english

Fichier:

PDF, 1.66 MB

english, 2012

13

ATP Binding and Hydrolysis-Driven Rate-Determining Events in the RFC-Catalyzed PCNA Clamp Loading Reaction

Miho Sakato, Yayan Zhou, Manju M. Hingorani

Journal:

Journal of Molecular Biology

Année:

2012

Langue:

english

Fichier:

PDF, 1.61 MB

english, 2012

14

Mechanism of Processivity Clamp Opening by the Delta Subunit Wrench of the Clamp Loader Complex of E. coli DNA Polymerase III

David Jeruzalmi, Olga Yurieva, Yanxiang Zhao, Matthew Young, Jelena Stewart, Manju Hingorani, Mike O'Donnell, John Kuriyan

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 1.34 MB

english, 2001

15

Recognition and Signaling in DNA Mismatch Repair: MD Studies of MutS Complexes with DNA and ATP

Pieniazek, Susan N., Hingorani, Manju, Beveridge, David L.

Journal:

Biophysical Journal

Année:

2009

Langue:

english

Fichier:

PDF, 37 KB

english, 2009

16

Dynamical Allosterism in the Mechanism of Action of DNA Mismatch Repair Protein MutS

Pieniazek, Susan N., Hingorani, Manju M., Beveridge, D.L.

Journal:

Biophysical Journal

Année:

2011

Langue:

english

Fichier:

PDF, 1.54 MB

english, 2011

17

DnaN clamp zones provide a platform for spatiotemporal coupling of mismatch detection to DNA replication

Lenhart, Justin S., Sharma, Anushi, Hingorani, Manju M., Simmons, Lyle A.

Journal:

Molecular Microbiology

Année:

2013

Langue:

english

Fichier:

PDF, 1.33 MB

english, 2013

18

Escherichia coli Heptosyltransferase I: Investigation of Protein Dynamics of a GT-B Structural Enzyme

Czyzyk, Daniel J., Sawant, Shreya S., Ramirez-Mondragon, Carlos A., Hingorani, Manju M., Taylor, Erika A.

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 883 KB

english, 2013

19

Understanding the Kinetic Mechanism of MutS during Mismatch Recognition and Initiation of Repair

Sharma, Anushi, Hingorani, Manju

Journal:

Biophysical Journal

Année:

2013

Langue:

english

Fichier:

PDF, 37 KB

english, 2013

20

Finding the Right ‘Mis’Match: Millisecond Conformational Dynamics of MutS-DNA Complex During DNA Damage Recognition

Yogambigai, Velmurugu, Narayanan, Ranjani, Kuznetsov, Serguei V., Hingorani, Manju, Ansari, Anjum

Journal:

Biophysical Journal

Année:

2010

Langue:

english

Fichier:

PDF, 38 KB

english, 2010

21

E. Coli Heptosyltransferase I: Exploring Function and Dynamics to Create Better Inhibitors for GT-B Enzymes

Czyzyk, Daniel J., Liu, Cassie, Sawant, Shreya S., Hingorani, Manju, Taylor, Erika A.

Journal:

Biophysical Journal

Année:

2013

Langue:

english

Fichier:

PDF, 37 KB

english, 2013

22

Allosterism in Muts Proteins: How DNA Mismatch Recognition Signals Repair

Pieniazek, Susan N., Hingorani, Manju M., Beveridge, David L.

Journal:

Biophysical Journal

Année:

2011

Langue:

english

Fichier:

PDF, 39 KB

english, 2011

23

Towards the Kinetic Mechanism of S. cerevisiae MutLλ DNA Mismatch Repair Protein

Sharma, Anushi, Hingorani, Manju

Journal:

Biophysical Journal

Année:

2011

Langue:

english

Fichier:

PDF, 37 KB

english, 2011

24

Obituary

Li, Yan, Mukerji, Ishita, Hingorani, Manju

Journal:

Année:

1948

Langue:

english

Fichier:

PDF, 661 KB

english, 1948

25

Investigation of the Binding Interaction of S. cerevisiae MutS Homologs MSH2-MSH6 and MSH4-MSH5 with Holliday Junctions

Li, Yan, Mukerji, Ishita, Hingorani, Manju

Journal:

Biophysical Journal

Année:

2011

Langue:

english

Fichier:

PDF, 40 KB

english, 2011

26

Structure-Function Analysis of the S. Cerevisiae PCNA Clamp-An Essential Protein in DNA Metabolism

Zhou, Yayan, Hingorani, Manju

Journal:

Biophysical Journal

Année:

2011

Langue:

english

Fichier:

PDF, 37 KB

english, 2011

27

Global and Local Conformational Studies of Mismatched Duplex DNA Upon Msh2-Msh6 Binding by Steady-State and Time-Resolved Fluorescence

Li, Yan, Hingorani, Manju, Mukerji, Ishita

Journal:

Biophysical Journal

Année:

2013

Langue:

english

Fichier:

PDF, 37 KB

english, 2013

28

Slow Conformational Changes in MutS and DNA Direct Ordered Transitions between Mismatch Search, Recognition and Signaling of DNA Repair

Sharma, Anushi, Doucette, Christopher, Biro, F. Noah, Hingorani, Manju M.

Journal:

Journal of Molecular Biology

Année:

2013

Langue:

english

Fichier:

PDF, 1.62 MB

english, 2013

29

Recognition and Signaling in DNA Mismatch Repair: Interdomain Communication in T. Aquaticus Muts Proteins

Pieniazek, Susan N., Bhattacharyya, Moitrayee, Vishveshwara, Saraswathi, Hingorani, Manju, Beveridge, David L.

Journal:

Biophysical Journal

Année:

2010

Langue:

english

Fichier:

PDF, 53 KB

english, 2010

30

Kinetic Analysis of Arginine-Finger Motif Function in S. cerevisiae Clamp Loader

Sakato, Miho, O'Donnell, Mike, Hingorani, Manju M.

Journal:

Biophysical Journal

Année:

2009

Langue:

english

Fichier:

PDF, 44 KB

english, 2009

31

Kinetic Analysis of Interactions between MutS, MutL and DNA During Initiation of DNA Mismatch Repair

Sharma, Anushi, Hingorani, Manju

Journal:

Biophysical Journal

Année:

2014

Langue:

english

Fichier:

PDF, 42 KB

english, 2014

32

Global and Local Conformation of Mismatched Duplex DNA Upon MSH2-MSH6 Binding Studied by Steady-State and Time-Resolved Fluorescence

Li, Yan, Hingorani, Manju, Mukerji, Ishita

Journal:

Biophysical Journal

Année:

2014

Langue:

english

Fichier:

PDF, 104 KB

english, 2014

33

The dTTPase Mechanism of T7 DNA Helicase Resembles the Binding Change Mechanism of the F1-ATPase

Manju M. Hingorani, M. Todd Washington, Kristen C. Moore and Smita S. Patel

Journal:

Proceedings of the National Academy of Sciences

Année:

1997

Langue:

english

Fichier:

PDF, 1.38 MB

english, 1997

34

Interactions of bacteriophage T7 DNA primase/helicase protein with single-stranded and double-stranded DNAs

Hingorani, Manju M., Patel, Smita S.

Journal:

Année:

1993

Langue:

english

Fichier:

PDF, 2.05 MB

english, 1993

35

The K318A Mutant of Bacteriophage T7 DNA Primase-Helicase Protein Is Deficient in Helicase But Not Primase Activity and Inhibits Primase-Helicase Protein Wild-Type Activities by Heterooligomer Formation

Patel, Smita S., Hingorani, Manju M., Ng, Winnie M.

Journal:

Année:

1994

Langue:

english

Fichier:

PDF, 4.02 MB

english, 1994

36

Cooperative Interactions of Nucleotide Ligands Are Linked to Oligomerization and DNA Binding in Bacteriophage T7 Gene 4 Helicases †

Hingorani, Manju M., Patel, Smita S.

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 525 KB

english, 1996

37

Asymmetric ATP Binding and Hydrolysis Activity of the Thermus aquaticus MutS Dimer Is Key to Modulation of Its Interactions with Mismatched DNA †

Antony, Edwin, Hingorani, Manju M.

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 279 KB

english, 2004

38

Mismatch Recognition-Coupled Stabilization of Msh2-Msh6 in an ATP-Bound State at the Initiation of DNA Repair †

Antony, Edwin, Hingorani, Manju M.

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 266 KB

english, 2003

39

Structure of a Mutant Form of Proliferating Cell Nuclear Antigen That Blocks Translesion DNA Synthesis †‡

Freudenthal, Bret D., Ramaswamy, S., Hingorani, Manju M., Washington, M. Todd

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 3.61 MB

english, 2008

40

Mechanism of Cadmium-Mediated Inhibition of Msh2-Msh6 Function in DNA Mismatch Repair

Wieland, Markus, Levin, Mikhail K., Hingorani, Karan S., Biro, F. Noah, Hingorani, Manju M.

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 1.97 MB

english, 2009

41

Distinct Structural Alterations in Proliferating Cell Nuclear Antigen Block DNA Mismatch Repair

Dieckman, Lynne M., Boehm, Elizabeth M., Hingorani, Manju M., Washington, M. Todd

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 4.21 MB

english, 2013

42

Bacteriophage T7 Helicase/Primase Proteins Form Rings Around Single-Stranded DNA that Suggest a General Structure for Hexameric Helicases

Edward H. Egelman, Xiong Yu, Robert Wild, Manju M. Hingorani and Smita S. Patel

Journal:

Proceedings of the National Academy of Sciences

Année:

1995

Langue:

english

Fichier:

PDF, 747 KB

english, 1995

43

MutL traps MutS at a DNA mismatch

Qiu, Ruoyi, Sakato, Miho, Sacho, Elizabeth J., Wilkins, Hunter, Zhang, Xingdong, Modrich, Paul, Hingorani, Manju M., Erie, Dorothy A., Weninger, Keith R.

Journal:

Proceedings of the National Academy of Sciences

Année:

2015

Langue:

english

Fichier:

PDF, 1.32 MB

english, 2015

44

4 NSF opportunities: a program director’s perspective

Hingorani, Manju

Journal:

Journal of Biomolecular Structure and Dynamics

Année:

2015

Langue:

english

Fichier:

PDF, 409 KB

english, 2015

45

11 Checkpoints controlled by PCNA, DNA and ATP direct the timing and order of events in the clamp loading mechanism

Liu, Juan, Hingorani, Manju M.

Journal:

Journal of Biomolecular Structure and Dynamics

Année:

2015

Langue:

english

Fichier:

PDF, 409 KB

english, 2015

46

116 Binding dynamics of yeast MutS homologs Msh4-Msh5 with the Holliday junction

Lahiri, Sudipta, Hingorani, Manju, Mukerji, Ishita

Journal:

Journal of Biomolecular Structure and Dynamics

Année:

2015

Langue:

english

Fichier:

PDF, 411 KB

english, 2015

47

Saccharomyces Cerevisiae Msh2-Msh6 DNA Binding Kinetics Reveal a Mechanism of Targeting Sites for DNA Mismatch Repair

Jie Zhai, Manju M. Hingorani and Eric E. Alani

Journal:

Proceedings of the National Academy of Sciences

Année:

2010

Langue:

english

Fichier:

PDF, 1.44 MB

english, 2010

48

Mismatch binding, ADP–ATP exchange and intramolecular signaling during mismatch repair

Hingorani, Manju M.

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 2.03 MB

english, 2015

49

Binding Dynamics of the Holliday Junction with Yeast MutS Homolog Msh4-Msh5

Lahiri, Sudipta, Hingorani, Manju, Mukerji, Ishita

Journal:

Biophysical Journal

Année:

2015

Langue:

english

Fichier:

PDF, 44 KB

english, 2015

50

Enhanced Dynamics of Mismatched Base Pairs Associated with Msh2-Msh6 Recognition

Li, Yan, Hingorani, Manju, Mukerji, Ishita

Journal:

Biophysical Journal

Année:

2015

Langue:

english

Fichier:

PDF, 44 KB

english, 2015